Leonardo A Sechi Selected Research

Paratuberculosis (Johne's Disease)

10/2022	A rapid phage assay for detection of viable Mycobacterium avium subsp. paratuberculosis in milk.
9/2021	A Comparative Study on the Efficiency of Two Mycobacterium avium subsp. paratuberculosis (MAP)-Derived Lipopeptides of L3P and L5P as Capture Antigens in an In-House Milk ELISA Test.
1/2020	Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mouse model of antigen-induced arthritis.
10/2019	Association between Lipoprotein Levels and Humoral Reactivity to Mycobacterium avium subsp. paratuberculosis in Multiple Sclerosis, Type 1 Diabetes Mellitus and Rheumatoid Arthritis.
1/2019	Recombinant fusion protein of Heparin-Binding Hemagglutinin Adhesin and Fibronectin Attachment Protein (rHBHA-FAP) of Mycobacterium avium subsp. paratuberculosis elicits a strong gamma interferon response in peripheral blood mononuclear cell culture.
10/2018	High levels of antibodies against PtpA and PknG secreted by Mycobacterium avium ssp. paratuberculosis are present in neuromyelitis optica spectrum disorder and multiple sclerosis patients.
5/2018	Interferon regulatory factor 5 is a potential target of autoimmune response triggered by Epstein-barr virus and Mycobacterium avium subsp. paratuberculosis in rheumatoid arthritis: investigating a mechanism of molecular mimicry.
1/2018	Mycobacterium avium subspecies paratuberculosis and myelin basic protein specific epitopes are highly recognized by sera from patients with Neuromyelitis optica spectrum disorder.
1/2016	Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D.
5/2014	Epstein-Barr virus and Mycobacterium avium subsp. paratuberculosis peptides are cross recognized by anti-myelin basic protein antibodies in multiple sclerosis patients.

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Leonardo A Sechi Research Topics

Disease

37	Hypertension (High Blood Pressure) 01/2022 - 04/2002
23	Hyperaldosteronism (Conn Syndrome) 10/2020 - 06/2006
19	Essential Hypertension 01/2022 - 02/2003
17	Infections 01/2021 - 10/2003
16	Paratuberculosis (Johne's Disease) 10/2022 - 03/2008
16	Insulin Resistance 01/2022 - 11/2003
12	Multiple Sclerosis 04/2020 - 11/2013
10	Tuberculosis (Tuberculoses) 12/2011 - 10/2003
9	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2019 - 03/2010
9	Cardiovascular Diseases (Cardiovascular Disease) 10/2019 - 01/2007
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 01/2005
5	Hyperplasia 01/2022 - 12/2010
5	Rheumatoid Arthritis 11/2021 - 01/2018
5	Renal Insufficiency (Renal Failure) 10/2021 - 04/2002
5	Neuromyelitis Optica (Devic's Disease) 04/2020 - 10/2017
5	Adenoma (Adenomas) 12/2017 - 01/2008
5	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 11/2016 - 01/2013
5	Non-alcoholic Fatty Liver Disease 03/2013 - 01/2005
4	Left Ventricular Dysfunction 01/2022 - 10/2013
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2020 - 01/2015
4	Crohn Disease (Crohn's Disease) 10/2019 - 10/2005
4	Parkinson Disease (Parkinson's Disease) 01/2019 - 02/2016
4	Diastolic Heart Failure 11/2016 - 10/2013
4	Hyperinsulinism (Hyperinsulinemia) 07/2012 - 04/2002
3	Neoplasms (Cancer) 01/2022 - 01/2020
3	Vitamin D Deficiency 01/2022 - 03/2013
3	Hypertrophy 01/2022 - 01/2012
3	Hyperglycemia 12/2021 - 04/2005
3	Type 2 Diabetes Mellitus (MODY) 12/2021 - 01/2017
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2021 - 12/2018
3	Disease Progression 11/2021 - 12/2012
3	Obesity 04/2021 - 09/2007
3	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 03/2010
3	Thyroiditis 10/2019 - 01/2015
3	Albuminuria 12/2017 - 07/2007
3	Keratitis 06/2011 - 02/2004
2	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2021
2	Glucose Intolerance 01/2022 - 11/2013
2	COVID-19 01/2022 - 12/2020
2	Inflammation (Inflammations) 01/2019 - 04/2005
2	Primary Hyperparathyroidism 05/2018 - 01/2016
2	Virus Diseases (Viral Diseases) 01/2018 - 01/2016
2	Heart Failure 01/2017 - 01/2012

Drug/Important Bio-Agent (IBA)

23	AldosteroneIBA 05/2018 - 04/2005
18	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2005
14	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 04/2002
14	AntibodiesIBA 11/2021 - 05/2011
13	AntigensIBA 11/2021 - 01/2005
12	Insulin (Novolin)FDA Link 01/2022 - 11/2003
12	Peptides (Polypeptides)IBA 01/2020 - 05/2011
10	EpitopesIBA 01/2022 - 01/2014
10	ReninIBA 05/2018 - 07/2007
9	Mineralocorticoid Receptor AntagonistsIBA 10/2020 - 07/2007
7	Lipoprotein(a)IBA 10/2021 - 02/2003
5	CreatinineIBA 01/2022 - 04/2002
5	Virulence Factors (Pathogenicity Factors)IBA 10/2018 - 02/2004
5	SaltsIBA 01/2017 - 12/2003
5	ProinsulinIBA 01/2017 - 01/2015
5	Fibrinogen (Factor I)FDA Link 07/2015 - 12/2008
5	Spironolactone (Aldactone)FDA LinkGeneric 01/2013 - 06/2006
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2018
4	LipidsIBA 10/2021 - 01/2005
4	lipoarabinomannan (LAM)IBA 04/2020 - 03/2005
4	AlbuminsIBA 12/2017 - 06/2006
4	Hemostatics (Antihemorrhagics)IBA 01/2017 - 01/2013
4	N 30IBA 01/2016 - 12/2005
4	HomocysteineIBA 12/2015 - 01/2012
4	Fatty Acids (Saturated Fatty Acids)IBA 10/2015 - 01/2014
4	fibrin fragment D (D-dimer)IBA 10/2013 - 12/2008
4	AdiponectinIBA 03/2013 - 01/2005
4	DNA (Deoxyribonucleic Acid)IBA 08/2012 - 10/2003
3	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2019 - 01/2014
3	Parathyroid Hormone (Parathormone)IBA 05/2018 - 01/2016
3	Eplerenone (Inspra)FDA LinkGeneric 05/2018 - 01/2013
3	Plasminogen Activators (Plasminogen Activator)IBA 01/2016 - 01/2013
3	Antihypertensive Agents (Antihypertensives)IBA 06/2015 - 07/2007
3	Prothrombin (Factor II)IBA 10/2013 - 12/2008
3	Insulin ReceptorIBA 10/2011 - 11/2003
3	PotassiumIBA 01/2010 - 07/2007
2	AcidsIBA 10/2022 - 01/2021
2	hydroxide ionIBA 01/2022 - 03/2013
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022 - 09/2007
2	Glycoproteins (Glycoprotein)IBA 08/2021 - 10/2017
2	Interleukin-2 (IL2)IBA 04/2020 - 01/2018
2	Interferon Regulatory FactorsIBA 01/2020 - 01/2019
2	InterferonsIBA 01/2020 - 09/2016
2	Immunoglobulin G (IgG)IBA 01/2020 - 11/2013
2	Interferon-gamma (Interferon, gamma)IBA 01/2020 - 01/2019
2	AutoantibodiesIBA 10/2019 - 01/2019
2	Lipoproteins (Lipoprotein)IBA 10/2019 - 01/2015
2	MicroRNAs (MicroRNA)IBA 12/2018 - 01/2016
2	CytokinesIBA 05/2018 - 12/2011
2	Myelin Basic ProteinIBA 01/2018 - 05/2014
2	Zinc Transporter 8IBA 01/2016 - 01/2014
2	Natalizumab (Tysabri)FDA Link 01/2016 - 10/2015
2	25-hydroxyvitamin DIBA 06/2015 - 03/2013

Therapy/Procedure

12	Adrenalectomy 10/2020 - 06/2006
10	Aftercare (After-Treatment) 01/2020 - 06/2006
8	Therapeutics 10/2021 - 01/2006
3	Contact Lenses 06/2011 - 02/2004